2000

in one of her first TV appearances, Natasha Lyonne plays Grace's intern who, after meeting Karen, quickly becomes obsessed with her. Season 3, Episode 4 'Girl Trouble': Grace's (Debra Messing) delight in having a bright intern (guest star Natasha Lyonne, "Slums of Beverly Hills") whom she can mentor turns into horror when the young woman re-makes herself into the spitting image of sassy, brassy Karen (Megan Mullally) -- and that's at least one too many Karens to handle. Meanwhile, Will (Eric McCormack) and Jack (Sean Hayes) volunteer to act out scenes for a gay sensitivity seminar for the local police but the peaceful intent is lost when they tussle with two lesbian (guest stars Suzanne Krull and Henriette Mantel) cast members who strongly object to their non-inclusive, sexist language. Shelley Morrison also stars.

Natasha Lyonne on the "Tonight Show with Jay Leno" from July 14, 2000.